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目的:观察比较养阴平艾方水煎剂与免煎剂的疗效及安全性。方法:选择HIV感染者40例,随机分为治疗组18例和对照组22例。治疗组给予养阴平艾方免煎剂15g口服,一日二次;对照组给予养阴平艾方水煎剂150ml口服,一日二次,两组治疗周期均为3个月。结果:两组剂型中医症状积分、卡诺夫斯基积分、CD4+T淋巴细胞的比较差异无统计学意义。两组剂型患者血红蛋白、红细胞、白细胞、血小板、谷丙转氨酶、谷草转氨酶、肌酐、尿素氮的变化均在正常范围内,未见不良影响。结论:养阴平艾方水煎剂与免煎剂的疗效及安全性无显著差异,从方便服用,便于储藏、携带的角度考虑,免煎剂值得推广运用。
Objective: To observe and compare the efficacy and safety of Yanyinping Fang Fang Decoction and decoction. Methods: 40 HIV-infected patients were randomly divided into treatment group (n = 18) and control group (n = 22). The treatment group was given Yang Yinping Fang decoction 15g orally, twice a day; the control group was given Yang Yin Ping Fang decoction 150ml orally, twice a day, the two groups were treated for 3 months. Results: There was no significant difference in symptom score, Khanofsky score and CD4 + T lymphocyte between the two groups. The changes of hemoglobin, erythrocytes, leukocytes, platelets, alanine aminotransferase, aspartate aminotransferase, creatinine and urea nitrogen in the two dosage forms were within the normal range, with no adverse effects. Conclusion: There is no significant difference in efficacy and safety between yin yingping Ai Fang decoction and decoction. Considering the convenience of taking, easy storage and carrying, the decoction deserved to be promoted.