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目的：子宫腺瘤样瘤发生率低，在临床与病理上均易误诊和漏诊，病理上误诊漏诊的主要原因是其病理形态多样性以及与形态相似的其他肿瘤难鉴别。应用特殊染色和免疫组织化学染色对子宫腺瘤样瘤的诊断与鉴别诊断有重要意义。方法：从本院１０年档案材料１５６０例子宫良性肿瘤中共收集子宫腺瘤样瘤９例，观察其临床病理特征，选用细胞角蛋白（ＣＫ），波纹蛋白（ＶＩＭ），表皮膜抗原（ＥＭＡ），癌胚抗原（ＣＥＡ），血管相关因子（Ｆ８）和ＨＨＦ３５作为第一抗体，应用免疫组化方法（ＳＬＡＢ法），以及特殊染色如糖原染色（ＰＡＳ染色），嗜银染色（Ａｇ染色）和ＡｌｉｃｉａｎＢｌｕｅ染色（ＡＢ染色）。对每例进行染色，观察结果。结果：９例子宫腺瘤样瘤占１５６０例子宫良性肿瘤，其中６例误诊为其他肿瘤。免疫组化结果显示９例子宫腺瘤样瘤瘤细胞ＣＫ及ＶＩＭ均呈强阳性，而对ＣＥＡ，ＥＭＡ，Ｆ８及ＨＨＦ３５均无表达。ＡｌｃｉａｎＢｌｕｅ染色９例均有阳性反应，ＰＡＳ染色阴性，Ａｇ染色见瘤细胞周围银纤维少。结论：本文收集子宫腺瘤样瘤比以前文献报道发生率低，ＣＫ，ＶＩＭ及ＡｌｃｉａｎＢｌｕｅ染色是子宫腺瘤样瘤的阳性标记物，而ＣＥＡ，ＥＭＡ，ＨＨＦ３５，Ｆ８及ＰＡＳ染色瘤细?
Objective: The incidence of uterine adenomatoid tumors is low, and both clinical and pathological errors are often misdiagnosed and missed. The main reason for misdiagnosis due to pathology is its pathological diversity and difficult identification of other tumors with similar morphology. The application of special staining and immunohistochemical staining is of great significance in the diagnosis and differential diagnosis of uterine adenomatoid tumors. Methods: 9 cases of uterine adenomatoid tumors were collected from 1560 cases of benign tumors of the uterus in 10 years of archives of this hospital. The clinical and pathological features were observed. Cytokeratin (CK), corrugated protein (VIM) and epidermal membrane antigen (EMA) were used. , Carcinoembryonic Antigen (CEA), Vascular Related Factors (F8) and HHF35 as primary antibodies, immunohistochemical method (SLAB method), special staining such as glycogen staining (PAS staining), silver staining (Ag staining) And AliciaBlue staining (AB staining). Stain each case and observe the results. Results: Nine cases of uterine adenomatoid tumors accounted for 1,560 cases of benign uterine tumors, of which 6 cases were misdiagnosed as other tumors. The results of immunohistochemistry showed that 9 cases of uterine adenomatous tumor cells showed strong positive CK and VIM, but no expression of CEA, EMA, F8 and HHF35. AlcianBlue staining showed positive reaction in all 9 cases, and PAS staining was negative. Ag staining showed less silver fibers around the tumor cells. Conclusion: The incidence of uterine adenomatoid tumors collected in this study is lower than previously reported. CK, VIM and AlcianBlue staining are positive markers for uterine adenomatoid tumors. CEA, EMA, HHF35, F8, and PAS stains are fine.