论文部分内容阅读
人类肠道内菌群为人体内最大的内毒素池人体本身因素、外界环境因素及菌群自身因素对肠道菌群的动态平衡均有着不同的影响,当肠道菌群的动态平衡失衡时人类健康将造成危害。抗生素的应用恢复肠道菌群的失衡在一定程度上起着不可或缺的作用,但抗生素药物影响致病菌的同时,也会影响肠道内的正常菌群。对肠道内细菌菌群的影响以及影响的程度,取决于相关抗生素药物的抗菌谱系、给药的途径(口服、静脉、体外等)、给药的方式、肠道内抗生素药物的浓度等。肠道内菌群之间的相互作用也影响着抗生素药物对机体所起的作用道本身也是人体内最大的免疫器官,如抗生素药物与肠道菌群之间可以达到最佳的相互作用,将对人类健康的影响起着至关重要的作用。
Human intestinal flora is the largest body of endotoxin pool in the human body itself factors, external environmental factors and their own flora on the dynamic balance of the intestinal flora have different effects, when the dynamic balance of intestinal flora imbalance in human health Will cause harm. The application of antibiotics to restore the imbalance of intestinal flora to some extent play an indispensable role, but antibiotics affect pathogens, but also affect the normal intestinal flora. The effect on the bacterial flora in the intestine and the degree of its effect depend on the antibacterial lineage of the antibiotic drug concerned, the route of administration (oral, intravenous, in vitro, etc.), the mode of administration, the concentration of antibiotics in the intestine, and the like. The interaction between intestinal flora also affect the role of antibiotic drugs on the body Road itself is the body’s largest immune organ, such as antibiotics and intestinal flora can achieve the best interaction between the right The impact of human health plays a crucial role.