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应用近年来对小鼠肺上皮细胞性质研究的免疫学及放射性自显影术的资料以检验哺乳动物肺发生(即分成若干阶段)的传统方式。结果表明,所谈到的这种传统方式对小鼠是站不住的,很可能对其它的哺乳动物也是站不住。根据最近的资料,哺乳类动物肺发生的过程阐述如下:每一定型的肺其肺原基发育成由柱状上皮细胞衬覆的一些管状结构,称为原始小管。这个原基系统分化为两个明显
In recent years, immunological and autoradiographic studies of the nature of mouse lung epithelial cells have been used to test the traditional way of lung development in mammals (ie, divided into several stages). The results show that the traditional approach mentioned is indefensible for mice and is likely to stand up to other mammals as well. According to recent data, the process of lung development in mammals is illustrated as follows: The lung primordium of each of the stereotyped lungs develops into some tubular structure covered by columnar epithelial cells called the primitive tubule. The primordial system is differentiated into two distinct ones