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作者报导25例成人自身免疫性血小板减少症(AT)患者,静脉注射大剂量IgG(0.4g/kg×5天)的研究结果:①对血小板的疗效。全部患者的血小板计数在治疗期间均较治疗前增高。早期组10例(病程短于16周),治疗前平均血小板计数为2万,治疗后第5天平均上升至18.3万;晚期组15例(病程长期持续),治疗前与治疗后第5天分别为1.9万和12.2万,二组相比无差异,但血小板升高,峰值与持续时间二组间有明显差异(P<0.001)。早期组输注后血小板计数持续升高,其峰值水平平均59.8万,以后缓慢下降,维持在正常范围,平均173天。由于此组10例患者中9例行脾
The authors report 25 patients with adult autoimmune thrombocytopenia (AT) patients, intravenous high-dose IgG (0.4g / kg × 5 days) findings: ① the efficacy of platelets. Platelet counts in all patients were higher during treatment than before treatment. In the early group, 10 patients (duration shorter than 16 weeks) had an average platelet count of 20000 before treatment and an average of 183,000 on the fifth day after treatment; 15 patients in the advanced group (long-term duration), 5 days before and after treatment 19,000 and 122,000 respectively. There was no difference between the two groups, but there was a significant difference (P <0.001) between platelet rise and peak and duration. In the early group, the platelet count continued to increase after infusion, with an average peak value of 598,000. After that, the platelet count decreased slowly and maintained within the normal range with an average of 173 days. Because of this group of 10 patients in 9 cases of spleen