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目的了解妊娠晚期孕妇B群溶血性链球菌(GBS)携带情况,并分析其影响因素。方法选取2015年6—12月在永康市妇幼保健院产检并入院分娩的孕35~37周单胎孕妇4 048人,检测GBS并分析GBS感染情况及影响因素。结果共检出GBS感染363例,感染率为8.97%。多因素Logistic回归分析结果显示,有糖尿病(OR=3.56,95%CI:2.83~4.48)、近1年尿路感染史(OR=1.84,95%CI:1.34~2.52)、近1年阴道炎史(OR=4.51,95%CI:3.62~5.30)、早产史(OR=1.70,95%CI:1.19~2.44),教育程度<10年(OR=1.30,95%CI:1.05~1.62)、孕前BMI≥25 kg/m2(OR=1.40,95%CI:1.00~1.96)、孕次>1(OR=1.36,95%CI:1.02~1.82)是妊娠晚期孕妇感染GBS的危险因素。结论应针对患有糖尿病、近1年有尿路感染史和阴道炎史、有早产史的妊娠晚期孕妇开展GBS筛查,以减少不良妊娠结局的发生。
Objective To understand the status of carriage of hemolytic streptococcus (Group B) GBS in the third trimester of pregnancy and analyze its influencing factors. Methods From April to December in 2015, 4 048 singleton pregnant women of maternal age 35-37 weeks were enrolled in hospital for maternity and childbirth in Yongkang City for maternity and child health care. The GBS was detected and the infection status and influencing factors were analyzed. Results A total of 363 cases of GBS infection were detected, the infection rate was 8.97%. Multivariate Logistic regression analysis showed that there was a history of urinary tract infection (OR = 1.84, 95% CI: 1.34-2.52), diabetes for one year (OR 3.56, 95% CI 2.83-4.48) (OR = 1.30, 95% CI: 1.05-1.62), educational history (OR = 4.51, 95% CI: 3.62-5.30), premature birth history (OR = 1.70, 95% CI: 1.19-2.44) Pre-pregnancy BMI≥25 kg / m2 (OR = 1.40, 95% CI: 1.00-1.96), gestational age> 1 (OR = 1.36,95% CI: 1.02-1.82) were the risk factors for GBS infection in pregnant women of late pregnancy. Conclusions Should be targeted at those with diabetes, nearly 1 year history of urinary tract infection and vaginitis, pregnant women with preterm birth in the third trimester of pregnancy GBS screening to reduce the incidence of adverse pregnancy outcomes.