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左旋多巴(L-dopa)与外周多巴脱坡酶抑制剂卡比多巴合用,仍然是临床上用于治疗帕金森氏病的首选药物。L-dopa被代谢为多巴胺(DA)和3-0一甲基多巴(3-OMD),DA则继续被单胺氧化酶代谢为3,4一二羟基苯乙酸(****C)。本文叙述用微渗析法阶同离子对反相液相色谱和电
L-dopa and peripheral dopbacterial inhibitors combined with carbidopa, is still the clinical choice for the treatment of Parkinson’s disease drugs. L-dopa is metabolized to dopamine (DA) and 3-0-methyldopa (3-OMD) while DA continues to be metabolized by monoamine oxidase to 3,4-dihydroxyphenylacetic acid (**** C). This article describes the use of micro-dialysis step by step ion-pair reversed-phase liquid chromatography and electricity