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已知高海拔人有许多与低海拔人不同的生理特点,包括肺容量和肺顺应性增加。作者对海拔3600m地区34例和海拔400m地区36例刚出生1天的两组新生儿作了呼吸系统顺应性、通气量和胸壁变形指数测定。结果:海拔4OOm组呼吸系统顺应性与以往报道的低海拔新生儿相似,但海拔3600m组呼吸系统顺应性大于海拔400m组的33%,呼吸系统顺应性/kg大于37%(P<0.001);肺通气量和胸壁变形率,高海拔组较低海拔组均轻度增加,但有显著性差异。提示通气驱动增加。作者认为,高海拔人呼吸系统顺应性增大的原因:①出生时就存在;②不是遗传;③胎儿缺氧是非常关键的因素。
It is known that many people at high altitudes have different physiological characteristics from those at lower altitudes, including increased lung capacity and lung compliance. The authors measured respiratory compliance, ventilation, and chest wall deformity index for two groups of 36 newborns at 3600 m above sea level and 36 at 1 400 m altitude. Results: Respiratory compliance at 4OOm above sea level was similar to that of the previously reported low - altitude newborns. However, the respiratory compliance at 3600m above sea level was significantly higher than that at 400m altitude (33%) and respiratory compliance (37%) (P <0.001). Lung ventilation and chest wall deformation rate, high altitude group lower altitude group were slightly increased, but there was a significant difference. Tip ventilation increases. The author believes that high altitude respiratory system due to increased compliance: ① exist at birth; ② is not genetic; ③ fetal hypoxia is a very crucial factor.