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目的比较头孢匹胺组合物与头孢哌酮舒巴坦钠治疗儿童社区获得性肺炎的疗效。方法细菌性肺炎患儿90例,随机分为三组:A组使用头孢哌酮舒巴坦钠80mg/kg,B组使用头孢匹胺组合物50mg/kg,C组使用头孢匹胺50mg/kg;均以静脉滴注给药,每8小时1次。比较三组患儿的临床疗效。结果三组的临床有效率均为100%。B组体温恢复时间、肺部啰音消失时间和住院天数分别为(1.2±1.5)d、(4.4±2.3)d和(6.7±1.5)d,均明显短于A和C组的(1.8±1.8)d和(1.6±1.4)d、(5.9±3.6)d和(5.9±3.1)d和(10.2±3.5)d和(10.5±2.7)d(P<0.05)。结论头孢匹胺组合物与头孢哌酮舒巴坦钠治疗儿童细菌性肺炎均疗效显著,其中头孢匹胺组合物治疗显效更快,患儿住院时间更短,不良反应发生率低。
Objective To compare the efficacy of cefpiramide and cefoperazone sulbactam in children with community-acquired pneumonia. Methods Ninety children with bacterial pneumonia were randomly divided into three groups: group A received cefoperazone sulbactam sodium 80mg / kg, group B received cefpiramide 50mg / kg, group C received cefpiramide 50mg / kg ; Are administered intravenously, every 8 hours 1. The clinical efficacy of three groups were compared. Results The clinical efficacy of the three groups were 100%. The time of recovery of body temperature, disappearance of pulmonary rales and days of hospital stay in group B were (1.2 ± 1.5) days, (4.4 ± 2.3) days and (6.7 ± 1.5) days, respectively, which were significantly shorter than those in groups A and C (1.8 ± 1.8 d and 1.6 ± 1.4 d, 5.9 ± 3.6 d and 5.9 ± 3.1 d and 10.2 ± 3.5 d and 10.5 ± 2.7 d, respectively (P <0.05). Conclusion Cefoperazone and cefoperazone sulbactam sodium have significant efficacy in the treatment of bacterial pneumonia in children. Among them, cefpiramide is effective in treating patients with a shorter hospital stay and a lower incidence of adverse reactions.