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对一个新药的评价主要分为临床前评价和临床评价两部分,而要开展临床评价必须先进行临床前药理实验对药物进行临床前评价。临床前药理包括药效学、药物代谢动力学和毒理学的评价。临床前药理主要是在动物身上进行药理学和毒理学研究,动物实验的结果在一定程度上可以推论到人。世界卫生组织在《临床前药物安全实验的原则》材料中说:“很多药理作用在动物和人是一样的,动物实验的结果预示性很高,很多毒性作用
The evaluation of a new drug is mainly divided into two parts: pre-clinical evaluation and clinical evaluation. To carry out clinical evaluation, preclinical pharmacological experiments must be carried out before the clinical evaluation of the drug. Preclinical pharmacology includes pharmacodynamics, pharmacokinetics and toxicology evaluation. Preclinical pharmacology is mainly carried out in animal pharmacology and toxicology studies, the results of animal experiments to a certain extent, it can be inferred to humans. According to the “Principle of preclinical drug safety experiments”, WHO said: "Many pharmacological effects are the same in animals and humans. The results of animal experiments are highly predictable and have many toxic effects