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母乳喂养已被列为新生儿出血性疾病发病机制的一个重要因素,但其在新生儿期后凝血异常中的作用却很少知道。牛奶中的维生素K(下称维K)浓度大约是母乳的4倍以上。维生素K依赖凝集因子(简称V_kDCF)在正常足月婴儿是减少的,在未成熟儿则更少。伴有临床出血的V_kDCF缺乏在1个月以上的婴
Breastfeeding has been cited as an important factor in the pathogenesis of neonatal hemorrhagic disease, but its role in clotting abnormalities in the neonatal period is poorly understood. Milk vitamin K (hereinafter referred to as vitamin K) concentration is about 4 times more than breast milk. Vitamin K dependent agglutination factor (V_kDCF) is reduced in normal term infants and less in immature infants. V_kDCF with clinical bleeding is less than one month old