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灭滴灵已在产科用于防治厌氧菌感染。我们采用高效液相色谱仪测定产妇分娩后静脉和脐带血中灭滴灵浓度,从而分析药物的胎盘转运。产妇32人,平均年龄27岁。剖腹产15人,余为阴道分娩。分娩前口服灭滴灵400mg,分娩后立即取样。服药后半小时内未能检出药物,至40分钟时一例静脉血和脐
Metronidazole has been used in obstetric control of anaerobic infections. We measured the concentration of metronidazole in the veins and umbilical cord blood after maternal delivery using a high-performance liquid chromatograph to analyze the drug’s placental transport. 32 maternal, average age 27 years old. Caesarean section 15, I vaginal delivery. Before oral delivery metronidazole 400mg, immediately after delivery sampling. Within half an hour after taking the medication failed to detect the drug, to 40 minutes when a case of venous blood and umbilical