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目的研究重症肺炎患儿血小板数目及凝血功能的改变和临床意义。方法比较92例重症肺炎患儿与70例非重症肺炎患儿血小板数目(PLT)以及凝血功能组合包括凝血酶原时间(PT)、部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)、D-二聚体(DDI)检测结果并进行分析。结果重症组与非重症组比较,PLT差异无统计学意义(P>0.05),PT、APTT、TT和DDI升高,FIB降低,两组比较差异有统计学意义(P<0.01)。结论重症肺炎患儿易出现凝血功能障碍,检测肺炎患儿凝血功能可尽早判定病情严重程度。
Objective To study the changes and clinical significance of platelet count and coagulation function in children with severe pneumonia. Methods The PLT and PLT in 92 children with severe pneumonia and 70 children with non-severe pneumonia were compared. Prothrombin time (PT), partial thromboplastin time (APTT), thrombin time (TT) Fibrinogen (FIB), D-dimer (DDI) test results and analysis. Results There was no significant difference in PLT between severe group and non-severe group (P> 0.05). PT, APTT, TT, DDI and FIB decreased. There was significant difference between the two groups (P <0.01). Conclusions In children with severe pneumonia, coagulation dysfunction is easy to occur. Detecting the coagulation function of children with pneumonia can determine the severity of the disease as soon as possible.