论文部分内容阅读
一氧化氮(nitric oxide,NO)是一种新型的细胞内和细胞间的信使性气体物质,也是一种活性很强的气体分子自由基。在中枢神经系统(CNS),NO是目前研究的热点之一。 生长抑素(somatostatin,SS)广泛分布于下丘脑、CNS、胃肠道、肾脏及多种腺体中。CNS神经元分泌的SS通过影响许多神经肽和神经递质的释放和代谢,参与认知、痛觉、行为、运动等诸多功能的调节。近年来发现,SS也是一种神经介质,对神经活动有兴奋或抑制作用,参与癫痫的发病。
Nitric oxide (NO) is a new type of intracellular and intercellular messenger gas substances, but also a highly active gas molecules free radicals. In the central nervous system (CNS), NO is one of the hot spots of current research. Somatostatin (SS) is widely distributed in hypothalamus, CNS, gastrointestinal tract, kidney and various glands. The SS secreted by CNS neurons is involved in the regulation of many functions such as cognition, pain, behavior and movement by affecting the release and metabolism of many neuropeptides and neurotransmitters. In recent years found that SS is also a nerve mediator, the excitement or inhibition of nerve activity, involved in the incidence of epilepsy.