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肠癌是常见的恶性肿瘤,部分患者就诊时已经是晚期,失去手术机会,即使行手术切除也有近半数患者发生复发、转移。近年研究表明,化疗能控制晚期肠癌症状,延长生存时间,维持或提高患者的生存质量。FOLFOX6方案(甲酰四氢叶酸钙(CF)、草酸铂(LOHP)、5-氟尿嘧啶(5-FU))化疗已经被推荐为晚期肠癌患者的标准化疗方案之一,但其治疗效果并不理想,且
Colorectal cancer is a common malignancy. Some patients are already advanced at the time of treatment and lose the chance of surgery. Even if surgery is performed, nearly half of the patients have recurrence and metastasis. Recent studies have shown that chemotherapy can control the symptoms of advanced cancer, prolong survival, maintain or improve the quality of life of patients. The FOLFOX6 regimen (calcium folinate (CF), oxaliplatin (LOHP), and 5-fluorouracil (5-FU)) chemotherapy has been proposed as one of the standard chemotherapy regimens for patients with advanced colorectal cancer, but its therapeutic effect is not Ideal, and