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目的评估去甲肾上腺素治疗重症肝炎并发肝肾综合征患者的疗效。方法收集广西区南溪山医院肝病科自2005年来住院的33例重症肝炎并发肝肾综合征病例,在内科综合治疗基础上随机分为肾上腺素治疗组与对照组,对其病例的实验室指标以及疗效等进行分析。结果治疗后,NA组的Cr与BUN值均显著低于对照组(P<0.05),而尿量显著高于对照组(P<0.05),NA组显效率与对照组相比差异有统计学意义χ2=5.107,P=0.027。结论去甲肾上腺素对于重症肝炎并发肝肾综合征的疗效较好,性价比高,值得推广。
Objective To evaluate the efficacy of norepinephrine in the treatment of patients with severe hepatitis and hepatorenal syndrome. Methods A total of 33 cases of severe hepatitis complicated with hepatorenal syndrome admitted to Department of Hepatology, Nanxi Mountain Hospital of Guangxi Zhuang Autonomous Region from 2005 were randomly divided into adrenaline treatment group and control group on the basis of comprehensive medical treatment. The laboratory indexes of their cases And efficacy analysis. Results After treatment, the values of Cr and BUN in NA group were significantly lower than those in control group (P <0.05), and the urine volume was significantly higher than that in control group (P <0.05). The difference between NA group and control group was statistically significant Significance χ2 = 5.107, P = 0.027. Conclusion Norepinephrine has a good curative effect on severe hepatitis with hepatorenal syndrome, which is worthy of promotion.