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RECOMB 2013 was successfully held in Tsinghua University,Beijing,China on April 7-10,2013,hosted by the Bioinformatics Division and Center for Synthetic and Systems Biology,Tsinghua National Laboratory for Information Science and Technology (TNLIST).A total of about 500 professionals from both academia and industry from 29 countries and regions attended the conference and its RECOMB-Seq satellite workshop after the main conference.