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患者13岁。因功能性子宫出血合并血小板无力症曾3次住我院治疗,报道如下。第一次住院:1991年2月4日月经初潮量多,伴头晕气短,血红蛋白最低50g/L,外院诊断功能性子宫出血,用雌激素高达12g/日,10天后血止。3月12日肌内注射黄体酮10mg/日,共5天,3月16日停药,3月17日因出血量多晕厥,于1991年3月21日急诊入我院。患者1岁半时因舌破出血不止,4及9岁因牙龈出血不止,均经输血及药物治疗后血止。平时皮肤易发生出血点及瘀斑。无外伤及药物过敏史。父母体健,非近亲婚配,均无出血倾向。祖母皮肤有出血点。一舅舅小时常鼻衄。家族中无血友病、白血病等病史。查体:脉搏、血压正常、皮肤苍白,巩膜无黄染。乳房发育Ⅳ级,心肺(一),肝脾未触及。腹部与下肢少许散在陈旧性出血点,右下肢皮肤瘀斑。外阴发育正常,
The patient is 13 years old. Due to functional uterine bleeding with thrombocytopenia had 3 times live in our hospital, reported as follows. The first hospitalization: February 4, 1991 the amount of menarche, with dizziness shortness of breath, hemoglobin lowest 50g / L, the hospital diagnosed functional uterine bleeding, with estrogen up to 12g / day, 10 days after blood only. March 12 intramuscular injection of progesterone 10mg / day, a total of 5 days, March 16 withdrawal, March 17 due to more amount of blood loss syncope, in March 21, 1991 emergency department into our hospital. Patients at 1 year and a half due to tongue bleeding more than 4 and 9 years old due to bleeding gums, both after blood transfusion and drug treatment of blood only. Usually prone to skin blemishes and ecchymosis. No history of trauma and drug allergy. Parents physical health, non-relatives marriage, no bleeding tendency. Grandmother skin bleeding. A uncle often nosebleed. Family no hemophilia, leukemia and other medical history. Physical examination: pulse, normal blood pressure, pale skin, sclera no yellow dye. Breast Ⅳ, heart and lung (a), liver and spleen not touched. Abdomen and lower extremity scattered a little old bleeding point, right lower extremity ecchymosis. Genital development is normal,