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目前骨髓移植的研究包括组织相容性抗原的遗传,寻找预防宿主免疫排斥的免疫抑制方案和移植物抗宿主病(GVHD)的防治方法等三方面。著者认为若能提供骨髓相容的供体,则骨髓移植对重型再生障碍性贫血治疗效果较好,西雅图系移植后长期生存的68例中,死于移植物排斥19例,死于GVHD16例,其他原因死亡2例,维持移植并血象恢复存活8月～5年者31例。著者指出受体淋巴细胞对供体细胞的反应性(混合白细胞培养指数(+)或Cr~(51)释放试验(+))和小量骨髓细胞移植对发生移
At present, researches on bone marrow transplantation include the inheritance of histocompatibility antigens, looking for immunosuppressive measures to prevent host immune rejection and prevention and treatment of graft versus host disease (GVHD). The author believes that if the donor can provide bone marrow compatibility, the treatment of severe acute aplastic anemia bone marrow transplantation is better, Seattle long-term survival after transplantation in 68 cases, died of graft rejection in 19 cases, died of GVHD in 16 cases, Other causes of death in 2 cases, to maintain the transplant and blood resumed survival in August to 5 years in 31 cases. The authors point out that reactivity of recipient lymphocytes to donor cells (mixed leukocyte culture index (+) or Cr (51) release assay (+)) and small bone marrow cell transplants