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综述影响胰腺癌切除术后生存时间的相关因素。性别、年龄对术后生存时间没有影响 ,肿瘤TNM分期、组织学类型、切缘阳性还是阴性与术后生存率关系密切。各种标准胰十二指肠切除术式的预后没有差别 ,对淋巴结阳性患者 ,扩大切除术的效果优于标准切除术 ,门静脉切除与否对术后生存时间无影响 ,但门静脉被癌组织侵犯者预后差。围手术期辅助治疗可以延长术后生存时间。肿瘤组织的某些分子生物学特征也与预后关系密切。
The related factors influencing survival time after resection of pancreatic cancer were reviewed. Sex and age had no effect on the postoperative survival time. The TNM stage, histological type, positive or negative margins and the postoperative survival rate were closely related. There is no difference in the prognosis of various types of pancreatoduodenectomy. For patients with positive lymph nodes, the effect of extended resection is better than standard resection. The resection of the portal vein has no effect on the survival time, but the portal vein is infiltrated by the cancer tissue Poor prognosis. Perioperative adjuvant therapy can prolong postoperative survival time. Some molecular features of tumor tissue are also closely related to the prognosis.