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最近几年γ-谷氨酰基转肽酶(γ-glutamyl transpeptidase,以下简称γ-GTP)在临床上的应用已渐被重视。早在30年前Hane等人就在绵羊的肾和胰脏的浸出液中发现一种特殊的转肽酶,后被Szewczuk等人在牛肾脏浸出液中所提纯,分子量为3×10~6。后来人们发现在人类或某些动物的血清和尿中也有这种酶,它能催化γ-L-谷氨酰基与其他肽或氨基转移,而被称为γ-谷氨酰基转肽酶。γ-GTP的活性可以
In recent years, γ-glutamyl transpeptidase (γ-glutamyl transpeptidase, hereinafter referred to as γ-GTP) in clinical applications has gradually been valued. As early as 30 years ago, Hane et al. Found a special transpeptidase in the leachate of sheep’s kidney and pancreas and was purified by Bovine kidney leachate by Szewczuk et al. At a molecular weight of 3 × 10 -6. Later, it was found that this enzyme was also found in the serum and urine of humans or certain animals, and it catalyzed the transfer of γ-L-glutamyl to other peptides or amino groups, and was called γ-glutamyl transpeptidase. γ-GTP activity can be