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现代医学的实验研究发现cAMP和cGMP在调节细胞功能上有着极为广泛而重要的作用。鉴于扶正中药的药理作用是多方面的,但主要在于调整机体失调的功能,使之趋向相对平衡。因此,研究扶正中药与环核苷酸系统的关系是值得注意的一项工作。又鉴于血浆环核苷酸基础水平较低,波动幅度大,药物或病理引起的差异往往不易显示,为此,我们建立了几种动物病理模型,以β-肾上腺素能激动剂(异丙基肾上腺素简称异丙)引起体内cAMP含量升高及M-胆矸能激动剂(氨甲酰胆矸简称氨甲)引起体内cGMP含量升高为指标,主要观察了
Experimental studies in modern medicine found that cAMP and cGMP play a very extensive and important role in regulating cell function. In view of the pharmacological effects of Chinese medicine Fuzheng is multifaceted, but the main function is to adjust the body disorders, so that the trend is relatively balanced. Therefore, it is worth noting that the study of the relationship between Chinese medicine and the Central Nucleotide System. In view of the low base level of plasma cyclic nucleotides and the large fluctuation range, the difference caused by drug or pathology is often not easy to be displayed. Therefore, we established several animal pathological models using β-adrenergic agonist (isopropyl Epinephrine referred to as isoproturine) caused by the increase of cAMP content in vivo and M-biliary gangrene agonist (carbamoylcholic ganglion referred to as ammonia methyl) caused by increased cGMP content as an indicator of the main observation