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目的观察臭氧联合乳杆菌胶囊治疗细菌性阴道炎的临床疗效。方法将细菌性阴道病患者共208例随机分为研究组和对照组,104例为研究组,用臭氧联合乳杆菌活菌胶囊治疗;104例为对照组,口服甲硝唑加阴道置入甲硝唑阴道泡腾片治疗,比较2组的治愈率、总有效率、复发率及药物的副反应。结果 2组患者治疗结果差异无统计学意义(P>0.05),但研究组比对照组总治愈率高;4周复发率12周复发率及半年复发率比较,研究组明显低于对照组,2组比较有显著性差异(P<0.01);2组药物副反应比较有显著性差异(P<0.01)。结论臭氧联合乳杆菌治疗细菌性阴道病既能杀菌又能改变阴道内环境,无毒副作用,痛苦小,不易复发,安全、有效。
Objective To observe the clinical efficacy of ozone combined with Lactobacillus capsule in the treatment of bacterial vaginosis. Methods A total of 208 patients with bacterial vaginosis were randomly divided into study group and control group, 104 cases were treated with Lactobacillus combined with Lactobacillus oocysts and 104 as control group. Metronidazole plus vaginal instillation Nitazoxanide vaginal effervescent tablets treatment, the cure rate, total effective rate, relapse rate and drug side effects were compared. Results There was no significant difference in the treatment outcome between the two groups (P> 0.05), but the total cure rate of the study group was higher than that of the control group. The recurrence rate of 4 weeks was significantly lower in 12 weeks and 6 months than in control group, There was significant difference between the two groups (P <0.01). There was significant difference between the two groups in side effects (P <0.01). Conclusion Ozone combined with Lactobacillus treatment of bacterial vaginosis can both sterilization but also change the vaginal environment, non-toxic side effects, little pain, difficult to relapse, safe and effective.