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目的分析克霉唑栓和伊曲康唑联合治疗霉菌性阴道炎的效果。方法选取我院2013年2月—2016年2月收治的霉菌性阴道炎患者136例作为研究对象,将其随机分为对照组和观察组各68例,对照组患者采用克霉唑栓治疗,观察组患者则在此基础上加用伊曲康唑进行治疗,对比2组治疗效果。结果对照组治疗总有效率为73.5%,明显低于观察组的94.1%(P<0.05);对照组复发率为11.8%,明显高于观察组的2.9%(P<0.05);2组不良反应发生率无显著差异(P>0.05)。结论与单纯使用克霉唑栓相比,伊曲康唑联合克霉唑栓联合治疗霉菌性阴道炎具有起效快、副作用小等优势,疗效更为显著,值得临床推广应用。
Objective To analyze the effect of clotrimazole suppository and itraconazole in the treatment of mycotic vaginitis. Methods A total of 136 mycotic vaginitis patients admitted to our hospital from February 2013 to February 2016 were selected as the study subjects. They were randomly divided into control group and observation group, 68 cases in each group. The control group was treated with clotrimazole suppository, Patients in the observation group were treated with itraconazole on the basis of this study, and the treatment effect was compared between the two groups. Results The total effective rate of the control group was 73.5%, significantly lower than that of the observation group (94.1%, P <0.05). The recurrence rate of the control group was 11.8%, significantly higher than that of the observation group (2.9%, P <0.05) No significant difference in the incidence of response (P> 0.05). Conclusion Compared with simply using clotrimazole suppository, itraconazole combined with clotrimazole suppository in the treatment of fungal vaginitis has the advantages of quick onset, small side effects, and more obvious curative effect, which is worthy of clinical application.