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回顾性比较孕早期11～14周与孕16～19周羊膜腔穿刺胎儿的预后。羊膜腔穿刺遗传检查由3位有经验的医生在超声指引下操作,每位医生每年羊膜腔穿刺约500例,孕早期11～14周穿刺者约有30～50例,传统的羊膜腔穿刺规定在孕14周以后。 孕妇近期有阴道流血或超声检查有血肿者不作孕早期羊膜腔穿刺,穿刺后随访30天并测甲胎蛋白和重复超声检查,每例抽羊水约25ml,两组均作细胞培养,所有孕妇均回原穿刺医生处作检查与分娩。 病例为1988年8月～1992年12月间的孕妇,分娩时年龄最小35岁、单胎。研究组为孕11～14周
The prognosis of amniocentesis was retrospectively compared between 11-14 weeks of gestation and 16-19 weeks of gestation. The amniocentesis genetic test by the three experienced doctors under the guidance of ultrasound operation, each doctor about 500 cases of amniocentesis each year during the first trimester 11 to 14 weeks about 30 to 50 cases of puncture, the traditional provisions of the amniocentesis After 14 weeks pregnant. Pregnant women with recent vaginal bleeding or ultrasound examination of the hematoma were not for early pregnancy amniocentesis, 30 days after puncture followed up and test for alpha-fetoprotein and repeat the ultrasound examination, each case of amniotic fluid about 25ml, both groups were cell culture, all pregnant women Back to the original puncture doctor for examination and childbirth. Cases of pregnant women between August 1988 ~ December 1992, the youngest 35-year-old childbirth, single birth. The study group was pregnant 11 to 14 weeks