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目的:优选并确立复方肾炎胶囊的最佳提取工艺。方法:采用水提工艺,以干浸膏得率、丹参酮Ⅱ_A含量为指标,通过L_9(3~4)正交试验对复方肾炎胶囊的水提工艺进行优化;建立了复方肾炎胶囊中丹参酮Ⅱ_A的含量测定方法。结果:复方肾炎胶囊水提最佳工艺条件为A_3B_3C_2,即每次加水8倍量,每次煎煮2 h,煎煮2次。结论:优选出的水提工艺经济,方法简单可行,提取率较高。
Objective: To optimize and establish the best extraction process of Compound Nephritis capsule. Methods: The water extraction process was used to optimize the water extraction process of compound nephritis capsule by the orthogonal experiment of L_9 (3 ~ 4) with the yield of dry extract and the content of tanshinone Ⅱ_A as the index. The tanshinone Ⅱ_A Determination of content. Results: The optimum conditions for the compound nephritis capsule water extraction were A_3B_3C_2, that is, adding 8 times of water each time, boiling for 2 hours and boiling twice. Conclusion: The optimized water extraction process is economical, the method is simple and feasible, and the extraction rate is high.