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[目的]探讨低剂量螺旋CT扫描引导下经皮肺穿刺活检术在诊断周围型肺癌中的应用价值。[方法]把60例CT引导下经皮肺穿刺活检患者随机分成两组,低剂量组30例行低剂量(130kV,30mA)CT扫描,常规剂量组30例行常规剂量(130kV,100mA)CT扫描,分别记录容积CT剂量指数(CTDIvol),并计算剂量长度积(DLP);统计两组相关指标:扫描范围、图像质量、活检阳性率、肺内针道出血发生率、咯血及气胸发生率,进行统计学分析。[结果]低剂量组CTDIvo1和DLP明显低于常规剂量组,差异有统计学意义(P<0.05)。两组的扫描范围、图像质量、活检阳性率、肺内针道出血、咯血及气胸发生率无显著性差异。[结论]低剂量(130kV、30mA)螺旋CT扫描引导下经皮肺穿刺活检既能保证穿刺成功和穿刺安全,又能显著减少患者的辐射剂量,是诊断周围型肺癌一种可行的方法。
[Objective] To investigate the value of percutaneous lung biopsy guided by low-dose spiral CT in the diagnosis of peripheral lung cancer. [Methods] 60 patients undergoing CT guided percutaneous lung biopsy were randomly divided into two groups. 30 patients underwent low dose (130kV, 30mA) CT scan in low dose group and 30 patients in conventional dose group received routine dose (130kV, 100mA) CT scan (CTDIvol), and calculate the dose-length product (DLP). The related indexes of the two groups were calculated: scanning range, image quality, positive rate of biopsy, the incidence of pulmonary hemorrhage, hemoptysis and pneumothorax incidence , For statistical analysis. [Result] CTDIvo1 and DLP in low dose group were significantly lower than those in conventional dose group, the difference was statistically significant (P <0.05). There were no significant differences in scan range, image quality, positive biopsy rate, intrapulmonary needle drainage, hemoptysis and pneumothorax incidence between the two groups. [Conclusion] Percutaneous lung biopsy guided by low dose (130 kV, 30 mA) spiral CT can not only ensure the puncture success and puncture safety but also reduce the radiation dose significantly. It is a feasible method to diagnose peripheral lung cancer.