论文部分内容阅读
视网膜色素变性(RP)是严重危害视功能的遗传性致盲眼病,至今病因不明,缺乏有效的治疗方法,因而成为防盲治盲中的重点疾病之一,RP作为一组单基因遗传病,与血型及HLA抗原等遗传标记的关系近年已引起注意。疾病与遗传标记间的连锁和关联分析不仅对探讨疾病的遗传病因学和发病机理有着重要的意义,而且利用遗传标记与疾病的伴随现象还可能预测乃至监控疾病的
Retinitis pigmentosa (RP) is a hereditary blind eye that seriously damages visual function. To date, the etiology is unknown and there is a lack of effective treatment methods. RP has become one of the most important diseases in blindness prevention and treatment. As a group of single-gene inherited diseases, The relationship with genetic markers such as blood type and HLA antigen has drawn attention in recent years. Linkage and association analysis of disease and genetic markers are of great importance not only for exploring the genetic aetiology and pathogenesis of the disease, but also for predicting and even monitoring the disease by using genetic markers and the attendant phenomena of the disease