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用流式细胞仪技术和ＭＴＴ法观察了云芝糖肽（ＰＳＰ）对由植物血凝素（ＰＨＡ）诱导的人外周血淋巴细胞（ＰＢＬ）增殖和Ｔ细胞亚群变化的调节作用。结果表明，５０～１００μｇ／ｍＬ ＰＳＰ对经ＰＨＡ诱导的人 ＰＢＬ增殖有显著的促进作用（Ｐ＜０． ０５），该浓度的ＰＳＰ也能促进细胞从Ｇ_１期进入Ｓ期，并可使ＣＤ_4~+细胞明显升高，使ＣＤ_4~+／ＣＬ_8细胞比例增加，提示ＰＳＰ具有免疫促进作用。
Flow cytometry and MTT assays were used to observe the effect of PSK on the proliferation of peripheral blood lymphocytes (PBL) and T lymphocyte subsets induced by phytohemagglutinin (PHA). The results showed that 50–100 μg/mL PSP significantly promoted the proliferation of human PBL induced by PHA (P<0.05). This concentration of PSP also promoted cells to enter S phase from G1 phase, and could also make CD_4~ The number of +cells was significantly increased, and the proportion of CD_4~+/CL_8 cells was increased, suggesting that PSP has an immunostimulating effect.