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目的 探讨复方丹参对小儿重症肺炎的疗效及血小板数 (PLT) ,容积 (MPV)和分布宽度 (PDW )的变化。方法 对 6 6例重症肺炎患儿和 5 0例健康小儿的PLT ,MPV和PDW进行了测定和比较 ,同时将血小板参数明显异常的患儿随机分为常规治疗组和丹参佐治组 ,后者在常规治疗的基础上加用复方丹参。结果 47例(71% )重症肺炎患儿的PLT ,MPV和 /或PDW明显异常其中 18例为伴有MPV和PDW升高的PLT降低 ;2 9例仅是MPV和PDW升高 ,PLT在正常范围。使用复方丹参可使异常的血小板恢复正常。患儿的临床症状、体征和并发症得以缓解 ,总有效率为 96 %。结论 血小板参数变化的检测有助于重症肺炎的预后评估 ,复方丹参佐治重症肺炎疗效较显著。
Objective To investigate the efficacy and the platelet count (PLT), volume (MPV) and distribution width (PDW) of compound Salvia miltiorrhiza in children with severe pneumonia. Methods The PLT, MPV and PDW in 66 children with severe pneumonia and 50 healthy children were measured and compared. At the same time, children with abnormal platelet parameters were randomly divided into routine treatment group and Salviae Miltiorrhiza group On the basis of conventional treatment plus compound Salvia. Results In 47 (71%) children with severe pneumonia, PLT, MPV and / or PDW were abnormally abnormal. Among them, 18 patients had PLT with elevated MPV and PDW, 29 patients only with elevated MPV and PDW, range. The use of compound Salvia can make abnormal platelets returned to normal. Children’s clinical symptoms, signs and complications were alleviated, the total effective rate was 96%. Conclusion The detection of changes in platelet parameters contributes to the prognosis evaluation of severe pneumonia. The efficacy of compound Danshen in treating severe pneumonia is significant.