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目的:观察双歧杆菌三联活菌散辅助治疗足月新生儿黄疸的疗效。方法:选取宁波市江东区艾博博尔妇产医院2014年9月至2015年8月新生儿科收治的黄疸新生儿共96例,均为足月儿,随机分为试验组和对照组各48例。对照组给予口服茵栀黄口服液每次3 m L,每日3次,同时蓝光治疗,每次10 h,每天1次;试验组在此基础上口服双歧杆菌三联活菌散,每次1.0 g,每天一次,两组均治疗5 d后比较临床疗效,并继续观察至黄疸完全消退。结果:试验组总有效率(93.8%)显著高于对照组(75.0%);试验组治疗后胆红素水平为(114.3±37.1)μmol/L,对照组治疗后胆红素水平为(228.6±18.4)μmol/L,两组比较差异有统计学意义(P<0.05);试验组黄疸消退时间为(7.3±2.2)d,对照组黄疸消退时间为(15.1±1.7)d,两组比较差异均有统计学意义(P<0.05)。结论:双歧杆菌三联活菌散辅助治疗足月新生儿黄疸疗效肯定,血清胆红素下降幅度大,所需治疗时间短,值得临床推广应用。
OBJECTIVE: To observe the curative effect of bifidobacterium triple active probiotics in the treatment of full-term neonatal jaundice. Methods: A total of 96 jaundice neonates were enrolled in neonatology department from April 2014 to August 2015 in Yiobol Maternity Hospital, Jiangdong District, Ningbo. All of them were full-term infants and were randomly divided into experimental group and control group example. The control group was given oral Yinzhihuang oral solution 3 m L each time, 3 times a day, while blue light treatment, every 10 h, 1 day; the experimental group on this basis oral Bifidobacterium triple viable bacteria, each time 1.0 g once a day, both groups were treated for 5 days after comparing the clinical efficacy, and continue to observe the complete regression of jaundice. Results: The total effective rate (93.8%) in the experimental group was significantly higher than that in the control group (75.0%). The bilirubin level in the experimental group was (114.3 ± 37.1) μmol / L after treatment and that in the control group was ± 18.4) μmol / L, the differences between the two groups were statistically significant (P <0.05). The jaundice subsided time was (7.3 ± 2.2) days in the experimental group and (15.1 ± 1.7) days in the control group, The differences were statistically significant (P <0.05). Conclusion: Bifidobacterium triple viable powder adjuvant treatment of full-term neonatal jaundice curative effect of positive, serum bilirubin decline in large, the required treatment time is short, worthy of clinical application.