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脑血管造影术及血管内介入治疗具有很好的安全性、诊断价值及治疗效果,已被广泛应用,但脑动脉血栓栓塞性闭塞仍然是其主要的并发症。动脉内局部溶栓术(LIF)在抢救急性基底动脉血栓形成中巳被广泛接受。由于经验有限,不同的病程和疾病的转归以及潜在致命的出血危险,LIF在脑的前循环血管闭塞的治疗中尚未被普遍接受。该研究通过回顾1983年～1994年所有经LIF治疗的医源性急性大脑中动脉(MCA)闭塞的病历及影像学资料评价了LIF的安全性及疗效。
Cerebral angiography and endovascular interventional therapy has good safety, diagnostic value and therapeutic effect. It has been widely used, but cerebral arterial thromboembolism occlusion is still the main complication. Intra-arterial local thrombolysis (LIF) has been widely accepted in the rescue of acute basilar artery thrombosis. LIF has not been universally accepted for the treatment of anterior circulation vascular occlusion of the brain due to limited experience, different course of disease and prognosis of the disease and the potentially fatal bleeding risk. The study evaluated the safety and efficacy of LIF by reviewing the medical records and imaging data of all iatrogenic acute middle cerebral artery occlusions treated with LIF from 1983 to 1994.