论文部分内容阅读
AIM:To investigate the clinical features,diagnosis,treatment and prognosis of multiple primary colorectalcarcinomas(MPCC).METHODS:A retrospective analysis of 37 patients withMPCC from 1974 to 1998 was carried out.RESULTS:The incidence of MPCC was 2.74%(37/1 348)in patients with primary colorectal carcinomas,15 casesof them were patients with synchronous carcinomas(SC)and 22 cases were diagnosed as metachronous carcinomas(MC).Most tumors were located in the right colon andrectum.Fifty-five percent(12122)of MC were diagnosedwithin 3 years after tumor resection and 41%(9/22)of MCoccurred after 8 years.Radical resections were performedin all patients except for 1 case.The 5-year survival rateof SC was 72.7%(8/11)and that of MC after the first cancerand second cancer was 71.4%(15/21)and 38.9%(7/18),respectively.CONCLUSION:The results indicate the importance ofcomplete preoperative examination,careful intraoperativeexploration and periodic postoperative surveillance.Earlydiagnosis and radical resection can increase survival rateof MPCC.
AIM: To investigate the clinical features, diagnosis, treatment and prognosis of multiple primary colorectal carcinomas (MPCC). METHODS: A retrospective analysis of 37 patients with MPCC from 1974 to 1998 was carried out .RESULTS: The incidence of MPCC was 2.74% (37 / 1 348) in patients with primary colorectal carcinomas, 15 cases of them were patients with synchronous carcinomas (SC) and 22 cases were diagnosed as metachronous carcinomas (MC) .Most tumors were located in the right colon and rectum. Fifty-five percent (12122) of MC were diagnosedwithin 3 years after tumor resection and 41% (9/22) of MCoccurred after 8 years. Radical resections were performed in all patients except for 1 case. The 5-year survival rate of SC was 72.7% (8/11) and that of MC after the first cancerand second cancer was 71.4% (15/21) and 38.9% (7/18), respectively.CONCLUSION: The results indicate the importance of complete preoperative examination, careful intraoperative growth and periodic postoperative surveillance. Early diagnosis and radica l resection can increase survival rate of MPCC.