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了解宫颈癌患者及对照患者宫颈组织中人乳头瘤病毒（HPV）与人巨细胞病毒（HCMV）的感染状况。应用聚合酶链反应方法检测宫颈新鲜活检组织HPV与HCMV。36例宫颈癌及38例子宫肌瘤患者的宫颈组织中，HPV合并入HCMV感染检测阴性率分别为2．8％和31.6％，HPV单独感染的检出率分别为25.0％和15.8％（P＜0.05），OR＝18.0；HCMV单独感染的检出率分别为83％和289％（P＞0.05），OR＝3．27；HPV合并HCMV感染的检出率分别为63.9％和30.7％（P＜0．01），OR＝30.7。在β-球蛋白基因阳性的27例宫颈癌及30例子宫肌瘤患者的宫颈组织中，HPV合并HCMV感染检测阴性率分别为3.7％和36.7％，HCMV单独感染的检出率分别为11.1％和20.0％（P＜0.05），OR=5．50。结论：HPV感染和江西的宫颈癌密切相关。HCMV感染可能在宫颈癌发生过程中与PIPV感染发生相关作用。
To understand the infection status of human papillomavirus (HPV) and human cytomegalovirus (HCMV) in cervical cancer patients and control patients. Polymerase chain reaction method was used to detect HPV and HCMV in fresh biopsies of cervix. In 36 cases of cervical cancer and 38 cases of uterine fibroids, the negative rates of HPV infection in HCMV infection were 2.8% and 31.6%, respectively. The positive rates of HPV infection were 25.0% and 15.8% (P The OR of HCMV infection was 83% and 289% (OR = 3.27, OR = 3.27, respectively), and the positive rate of HCMV infection was 63.9% and 30.7% P <0.01), OR = 30.7. In 27 cases of cervical cancer with β-globin gene and 30 cases of uterine fibroids, the negative rates of HPV infection with HCMV infection were 3.7% and 36.7%, respectively. The detection rates of HCMV infection alone were 11.1% And 20.0% (P <0.05), OR = 5.50. Conclusion: HPV infection and cervical cancer in Jiangxi are closely related. HCMV infection may be associated with PIPV infection during the development of cervical cancer.