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中枢性呼吸抑制(简称抑制)是新生儿破伤风(Neonatal Tetanus 简称NT)治疗中常见的严重并发症之一。我科1975～1987年共收治NT81例。治疗中出现抑制38例,占总数46.1%。死亡42例,其中死于抑制28例,占死亡总数的66.6%。临床资料81例患儿按治疗中是否出现抑制(包括全身反应低下、肌张力降低、刺激无抽搐、呼吸不规则和反复暂停)分为抑制组和未抑制组。抑制组38例,未抑制组43例。两组入院时病程及抽搐程度基本相似,在体重、早产及合并症诸方面无显著差别,P>0.05,具可比性。
Central respiratory depression (referred to as inhibition) is one of the most common complications of neonatal tetanus (Neonatal Tetanus referred to as NT) treatment. Our department from 1975 to 1987 were treated NT81 cases. Suppression of treatment appeared in 38 cases, accounting for 46.1% of the total. 42 cases died, of which 28 died of inhibition, accounting for 66.6% of the total deaths. Clinical data 81 patients were divided into inhibition group and non-inhibition group according to whether the treatment was inhibited (including low body reaction, hypotonia, stimulation without convulsion, irregular breathing and repeated pause). 38 cases in the inhibition group and 43 cases in the non-suppression group. Course of admission and convulsions of the two groups were basically similar in weight, premature birth and complications in all aspects of no significant difference, P> 0.05, comparable.