Hepatospheres : 三种维的房间文化类似于肝的生理的条件

• 作 者: Franziska van Zijl Wolfgang Mi
• 机 构: DepartmentofMedicineI
• 出 处: 世界肝病学杂志：英文版（电子版）
• 发表日期: 2010年1期
• 关键词: Hepatosphere HEPATOCYTE TISSUE ENGINEERING 3D CULTURE MICROENVIRONMENT Hepatosph
• 基金项目: Supported by the Austrian Science Fund,FWF,NO.P19598-B13 and SFB F28,the“Hochschuljubilumsstiftung der Stadt Wien”,the Herzfelder Family Foundation,the European Union,FP7 Health Research,NO.HEALTH-F4

Studying physiological and pathophysiological mechanisms in the liver on a molecular basis is a challenging task.During two dimensional(2D) culture conditions hepatocytes dedifferentiate rapidly by losing metabolic functions and structural integrity.Hence