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“盲”法原则是临床试验中减少偏倚的一种有效方法。包括:(1)“单盲”临床试验。研究者知道患者给药的具体内容,而患者不知道所接受治疗的真实内容。前者有利于保证患者在临床试验过程中的安全性,但不能避免研究者在实施治疗方案和评定疗效时所导致的偏倚。(2)“双盲”临床试验。研究者和患者都不知道所给治疗的真实内容,从而大大减少了来自这2方面的主观因素所造成的偏倚。双盲试验在实施中比较复杂,
The “blind” principle is an effective way to reduce bias in clinical trials. Including: (1) “single-blind” clinical trials. The researcher knows the specific content of the patient’s medication and the patient does not know the real content of the treatment they receive. The former is conducive to ensure the safety of patients in clinical trials, but can not avoid the researchers in the implementation of treatment options and assess the efficacy of the resulting bias. (2) “double-blind” clinical trials. Both the researcher and the patient do not know the true content of the treatment given, which greatly reduces the bias caused by subjective factors from these two aspects. Double-blind trial in the implementation of more complicated,