论文部分内容阅读
实验在沙土鼠短暂性脑缺血模型上应用含有PAF受体拮抗剂的FGP，以观察其对沙土鼠短暂性脑缺血后海马CA1区DND的影响。结果表明：沙土鼠双侧颈总动脉结扎10分钟再灌4天模型，与对照组相比，银杏叶制剂明显增加海马CA1区存活神经元数，分别为38．50±16．31／mm和133．13±20．99／mm（P＜0．01），与Nimodipine组（182±67／mm）结呆相近（P＞0．05）。提示：银杏叶制剂能明显对沙土鼠短暂性脑缺血后海马CA1区DND有保护作用。
To investigate the effects of FGP containing PAF receptor antagonist on DND in hippocampal CA1 area after transient cerebral ischemia in gerbils with transient ischemic brain damage model. The results showed that the gerbils bilateral common carotid artery ligation for 10 minutes and then for 4 days model, compared with the control group, Ginkgo biloba agents significantly increased the number of neurons in the hippocampal CA1 area were 38.50 ± 16.31 / mm and 133.13 ± 20.99 / mm (P <0.01), similar to the Nimodipine group (182 ± 67 / mm) (P> 0.05). Tip: Ginkgo biloba preparation can obviously protect the DND of hippocampal CA1 area after gerbil transient cerebral ischemia.