论文部分内容阅读
目的 :观察米非司酮治疗子宫肌瘤的临床效果。方法 :将 3 0例确诊为子宫肌瘤患者进行药物治疗 ,口服米非司酮12 5mgqd ,连服 3个月为一个疗程。治疗前后均行彩色超声监测子宫肌瘤大小 ,实验室观察卵泡刺激素 (FSH)、黄体生成素 (LH )、雌激素 (E2 )、孕酮 (P)、催乳素 (PRL)、雄激素 (T)。结果 :3 0例患者在治疗期间均出现闭经。子宫及子宫肌瘤体积均明显缩小 ,缩小率分别为 2 6 85 %和 45 68%(P <0 .0 1)。血FSHLHE2 P测定治疗后平均水平也较用药前下降 (P <0 .0 1)。其中以E2 和P下降最为显著 ,而PRL和T用药前后变化不明显。结论 :米非司酮治疗子宫肌瘤效果好 ,副反应小 ,是一种理想的治疗方法
Objective: To observe the clinical effect of mifepristone in treating uterine fibroids. Methods: 30 patients diagnosed with uterine fibroids in patients with medication, oral mifepristone 125mgqd, even for 3 months for a course of treatment. The size of uterine fibroids was monitored by color sonography before and after treatment. The levels of FSH, LH, E2, PR, androgen T). Results: Thirty patients had amenorrhea during the treatment. Uterine and uterine fibroids were significantly reduced volume, shrinkage rates were 2685% and 45 68% (P <0.01). The average level of serum FSHLHE2 P after treatment was also lower than before treatment (P <0.01). Among them, the decline of E2 and P was the most significant, while the changes of PRL and T before and after treatment were not obvious. Conclusion: Mifepristone treatment of uterine fibroids with good side effects, is an ideal method of treatment