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急性原始淋巴细胞白血病是以未成熟的淋巴细胞和祖细胞无控制的增生为特征的血液恶性疾病。急淋最常见于儿童,其次发生在青春期和成人。该病儿童治疗率为50—70％,与接受相同治疗的儿童相比,成人的缓解率较低,且短暂,存活期较短。分类按FAB分类,儿童急淋85％具有L1形态特征,L2或L3相对少见;成人急淋则L2占多数,L3偶见。白血病细胞的免疫学特征分类为:普通型、T细胞型、B细胞型和非T非B细胞表型。儿童急淋75％是普通表型,其余为T细胞或非T非B细胞表型;B细胞型相当罕见,低于1—
Acute primordial lymphocytic leukemia is a malignant disease of the blood characterized by uncontrolled proliferation of immature lymphocytes and progenitor cells. Acute leaching is most common in children, followed by puberty and adults. The treatment rate of children with this disease is 50-70%. Compared with children receiving the same treatment, the remission rate of adults is low, short-lived and short-lived. According to the FAB classification, 85% of children had an L1 morphological feature, and L2 or L3 were relatively rare. In adult acute leaching, L2 accounted for a majority and L3 occasionally. The immunological characteristics of leukemic cells were classified as: common, T-cell, B-cell, and non-T non-B cell phenotypes. 75% of children are acutely phenotypically phenotyped, and the rest are T-cell or non-T non-B cell phenotypes; B-cell types are rare and below 1—