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[目的]观察射频消融(RFA)联合化疗治疗结直肠癌肝转移的疗效。[方法]对22例不能手术的结直肠癌肝转移患者行经皮穿刺RFA及FOLFOX4化疗。[结果]22例57个病灶,完全坏死率81.82%,对坏死的判断,CT优于超声,中位无局部复发时间为232 d,中位生存期27个月,1年及2年生存率分别为91.2%及74.8%。[结论]RFA联合化疗治疗结直肠癌肝转移安全有效,值得进一步探索研究。
[Objective] To observe the curative effect of radiofrequency ablation (RFA) combined with chemotherapy on liver metastasis of colorectal cancer. [Method] Percutaneous RFA and FOLFOX4 chemotherapy were performed on 22 patients with unresectable colorectal cancer with liver metastasis. [Results] The complete necrosis rate was 81.82% in 22 cases with 57 lesions. CT was superior to ultrasound in determining necrosis. The median time to local recurrence was 232 days, and the median survival time was 27 months. The 1-year and 2-year survival rates Respectively 91.2% and 74.8%. [Conclusion] The combination of RFA and chemotherapy in the treatment of colorectal cancer liver metastasis is safe and effective, it is worth further exploration.