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目的探讨普萘洛尔治疗婴幼儿血管瘤溃疡的疗效。方法传统治疗组为2005年1月-2009年4月治疗婴幼儿血管瘤溃疡43例,以局部治疗为主;2009年5月-2011年6月治疗21例,在传统治疗方法的基础上给予口服普萘洛尔治疗,剂量为1.5～2.0mg/(kg·d),比较两组的疗效。结果两组患儿均被治愈,但普萘洛尔治疗组疗程(21.3±7.3d)明显短于传统治疗组(56.5±18.9d);且普萘洛尔治疗组局部瘢痕发生率(14.29%)明显低于传统治疗组(60.47%),以上差异均有统计学意义(P均<0.05)。结论婴幼儿血管瘤溃疡在传统局部创面治疗的基础上若给予口服普萘洛尔治疗,能加速患儿创面愈合和减少发生并发症。
Objective To investigate the effect of propranolol in the treatment of infantile hemangioma ulcer. Methods The traditional treatment group was 43 cases of infantile hemangioma ulcer from January 2005 to April 2009, with local treatment as the main treatment. From May 2009 to June 2011, 21 cases were treated, and on the basis of the traditional treatment methods Oral propranolol treatment, the dose of 1.5 ~ 2.0mg / (kg · d), the efficacy of the two groups were compared. Results The two groups of children were cured, but propranolol treatment group (21.3 ± 7.3d) was significantly shorter than the traditional treatment group (56.5 ± 18.9d); and propranolol treatment group local scar incidence (14.29% ) Was significantly lower than the traditional treatment group (60.47%), the above differences were statistically significant (P all <0.05). Conclusion Infantile hemangioma ulcer on the basis of the traditional local wound treatment given oral propranolol treatment can speed up the wound healing in children and reduce the occurrence of complications.