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目的:了解我院药品不良反应(ADR)发生情况,促进临床安全用药。方法:收集我院2008~2009年向国家药品不良反应报告中心上报的278例ADR报表,从患者年龄、性别,药品种类、给药途径,涉及器官以及临床表现、原发疾病,ADR的分类、结果判断等方面进行统计、分析。结果:278例ADR报表中,抗感染药引发ADR比例最高(72.15%),静脉给药构成比最高(84.89%),ADR的临床表现以皮肤及其附件损害为最多见(41.22%),新的严重的ADR 7例,判断结果中“很可能”、“可能”的比例最高。结论:加强对ADR监测力度及相关知识的宣传,确保临床安全用药。
Objective: To understand the incidence of adverse drug reaction (ADR) in our hospital and to promote clinical safe medication. Methods: A total of 278 cases of ADRs reported to the National Adverse Drug Reaction Reporting Center in our hospital from 2008 to 2009 were collected, including age, gender, type of drugs, route of administration, organs involved and clinical manifestations, primary diseases, ADR classification, The results of judgment and other aspects of statistics, analysis. Results: In the 278 cases of ADR, anti-infectives had the highest ADR (72.15%) and the highest IVV (84.89%). The clinical manifestation of ADR was the most common (41.22%) Of the serious ADR 7 cases, judging the results in the “most likely ”, “may ” the highest proportion. Conclusion: To strengthen the monitoring of ADR and related knowledge of publicity to ensure that clinical safe medication.