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目的探讨利凡诺尔联合米非司酮在瘢痕妊娠(CSP)中期引产中的应用效果。方法选取武汉市新洲区妇幼保健院2014年2月—2016年3月收治的CSP中期引产患者100例,随机分为对照组和试验组,各50例。对照组患者入院后进行常规消毒,给予利凡诺尔治疗;试验组患者在对照组基础上给予米非司酮治疗。观察比较两组患者引产成功率、子宫收缩时间、分娩时间、总产程、产后出血量及并发症发生情况。结果试验组患者引产成功率高于对照组,子宫收缩时间、分娩时间、总产程短于对照组,产后出血量少于对照组,且并发症发生率低于对照组(P<0.05)。结论采用利凡诺尔联合米非司酮可有效提高CSP中期患者引产成功率,缩短分娩时间和总产程,减少产后出血量和并发症发生。
Objective To investigate the effect of rivanol combined with mifepristone in induction of labor during the second trimester of pregnancy with scar (CSP). Methods A total of 100 patients with mid-term induction of labor in CSP who were treated in Xinzhou District Maternal and Child Health Hospital of Wuhan from February 2014 to March 2016 were randomly divided into control group and experimental group, with 50 cases in each group. Patients in the control group were routinely disinfected after admission and treated with Rivanol; patients in the test group were treated with mifepristone on the basis of the control group. Observe the success rate of induction of labor in two groups of patients, uterine contraction time, delivery time, total labor, postpartum hemorrhage and complications. Results The success rate of induction of labor in trial group was higher than that in control group. Uterine contraction time, delivery time and total labor duration were shorter than those in control group. Postpartum hemorrhage volume was less than control group. Complication rate was lower than that of control group (P <0.05). Conclusion Levanol combined with mifepristone can effectively improve the mid-term CSP rate of successful induction of labor, shorten the delivery time and total labor, reduce postpartum hemorrhage and complications.