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目的观察古拉定治疗药物性肝炎的临床疗效。方法将63例药物性肝炎患者随机分为2组,观察组32例给予古拉定600 mg静脉滴注治疗,对照组31例给予甘草酸二铵150 mg静脉滴注治疗。结果治疗后,观察组丙氨酸氨基转移酶、天门冬酸氨基转移酶、γ-谷氨酰转移酶水平均明显低于对照组(P<0.05);观察组治疗总有效率为90.62%,明显高于对照组的77.42%(P<0.05)。结论古拉定治疗药物性肝炎具有良好的效果,可有效改善患者肝功能,修复肝细胞组织,适合临床推广。
Objective To observe the curative effect of Gulandin on drug-induced hepatitis. Methods Sixty-three patients with drug-induced hepatitis were randomly divided into two groups. In the observation group, 32 cases were treated with GOLT 600 mg intravenously, while in the control group, 31 cases were given intravenous diammonium glycyrrhizinate 150 mg. Results After treatment, the levels of alanine aminotransferase, aspartate aminotransferase and γ-glutamyl transferase in the observation group were significantly lower than those in the control group (P <0.05). The total effective rate in the observation group was 90.62% Which was significantly higher than that of the control group (77.42%, P <0.05). Conclusion Gulandin treatment of drug-induced hepatitis has a good effect, which can effectively improve liver function, liver tissue repair, suitable for clinical promotion.