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目的;评价免疫球蛋白对重症手足口病的具体治疗方法和临床疗效。方法:选取六盘水市妇幼保健院2015年8月至2016年11月收治的重症手足口病患儿62例,分为观察组34例和对照组28例。两组患者均给予常规治疗方法,观察组在常规治疗的基础上加用人免疫球蛋白静脉滴注。对比两组患儿治疗48 h后的临床疗效。结果:两组患儿均治愈出院,未出现危重病例。观察组发热、惊跳消失时间等均显著短于对照组,差异具有统计学意义(P<0.05),观察组总有效率(94.12%)显著高于对照组(78.57%),差异具有统计学意义(P<0.05)。结论:重症手足口病患儿早期静脉注射人免疫球蛋白可明显改善临床症状,缩短住院时间,促进早期康复。
Objective To evaluate the specific immunoglobulin treatment of severe hand-foot-mouth disease and clinical efficacy. Methods: Sixty-two children with severe hand-foot-mouth disease who were admitted to Maternal and Child Health Hospital of Liupanshui City from August 2015 to November 2016 were divided into observation group (34 cases) and control group (28 cases). Two groups of patients were given conventional treatment, the observation group on the basis of routine treatment plus human immunoglobulin intravenous infusion. The clinical efficacy of the two groups of children after 48 hours of treatment was compared. Results: The two groups of children were cured and discharged without any serious cases. The fever in the observation group, the disappearance time of the asthenia were significantly shorter than those in the control group, the difference was statistically significant (P <0.05), the total effective rate (94.12%) in the observation group was significantly higher than that in the control group (78.57%), the difference was statistically Significance (P <0.05). Conclusion: Early intravenous injection of human immunoglobulin in children with severe hand-foot-mouth disease can significantly improve clinical symptoms, shorten the hospital stay and promote early rehabilitation.