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目的对比分析慢性阻塞性肺疾病患者急性加重期联合检测血清降钙素原、超敏C-反应蛋白的临床价值。方法选择焦作市妇幼保健院2013年6月至2014年6月期间收治的慢性阻塞性肺疾病患者共78例为研究对象,急性加重期共38例(观察组),稳定期40例(对照组),联合检测两组患者的血清降钙素原、超敏C-反应蛋白、血白细胞计数并进行对比分析。结果观察组患者的血清降钙素原、超敏C-反应蛋白显著高于对照组(P<0.05)差异显著具有统计学意义。观察组患者抗生素治疗7d后同治疗前对比差异显著(P<0.05)。结论慢性阻塞性肺疾病患者联合检测血清降钙素原、超敏C-反应蛋白能够提示患者处于急性加重期意义重大,对临床用药具有指导意义。
Objective To compare and analyze the clinical value of combined detection of serum procalcitonin and hypersensitive C-reactive protein in patients with chronic obstructive pulmonary disease during acute exacerbation. Methods A total of 78 patients with chronic obstructive pulmonary disease (COPD) treated in Jiaozuo MCH from June 2013 to June 2014 were enrolled in this study. Acute exacerbation was performed in 38 patients (observation group) and 40 patients (control group) ), Combined detection of two groups of patients serum procalcitonin, high-sensitivity C-reactive protein, white blood cell count and comparative analysis. Results The serum procalcitonin and hypersensitive C-reactive protein in observation group were significantly higher than those in control group (P <0.05), and the difference was statistically significant. The difference between the observation group and the control group after 7 days of treatment was significant (P <0.05). Conclusion Combined detection of serum procalcitonin and high-sensitivity C-reactive protein in patients with chronic obstructive pulmonary disease can be of great significance in patients with acute exacerbation, and is of guiding significance for clinical use.