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目的观察正常高值血压人群血清C反应蛋白(CRP)水平的变化,探讨炎症与高血压发生的关系。方法采用酶联免疫吸附法(ELISA)分别检测正常血压组(120例)、正常高值血压组(132例)和高血压组(124例)血清CRP水平。结果正常高值血压组CRP水平(3.25±1.43 mg/L)显著高于正常血压组(2.16±0.97 mg/L,P<0.01);高血压组(4.52±1.85 mg/L)又显著高于正常高值血压组(P<0.01)。结论CRP在正常高值血压时已开始升高,检测CRP有助于预测高血压的发生。
Objective To observe the changes of serum C-reactive protein (CRP) levels in people with normal high blood pressure and to explore the relationship between inflammation and hypertension. Methods Serum CRP levels were measured by enzyme-linked immunosorbent assay (ELISA) in 120 patients with normal blood pressure, 132 patients with normal high blood pressure and 124 patients with hypertension. Results The level of CRP in normal high blood pressure group (3.25 ± 1.43 mg / L) was significantly higher than that in normal blood pressure group (2.16 ± 0.97 mg / L, P <0.01) and hypertension group (4.52 ± 1.85 mg / L) Normal high blood pressure group (P <0.01). Conclusions CRP has started to increase at normal high blood pressure, and the detection of CRP can help predict the occurrence of hypertension.