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作者从日本卫生福利部的生命统计和临床记录收集的资料研究了1947—1986年破伤风死亡率及1947—1982年破伤风病例病死率趋势。1947—1986年期间,破伤风死亡病例22,401例,死亡率从1947年的2.84/10万人口(2,221例)降至1955年的0.98/10万人口(887例),1982年又进一步降至0.02/10万人口(26例)。新生儿破伤风死亡率下降的更快,从1947年的36.1/10万活产儿(972例)降至1970年的0.67(13例)到1979年已降至0,新生儿破伤风死亡率的快速下降与新生儿在医院出生代替在家出生呈现密切关系,在此期间没有对孕妇进行破伤风免疫。新生儿破伤风死亡率的降低促使破伤风总死亡率下降。
Based on data collected from the vital statistics and clinical records of the Ministry of Health and Welfare of Japan, the authors studied trends in tetanus mortality from 1947 to 1986 and cases of tetanus in 1947-1982. Between 1947 and 1986, there were 22,401 cases of tetanus deaths, with the death rate declining from 2.84 per 100,000 in 1947 (2,221 cases) to 0.98 per 100,000 in 1955 (887 cases) and further to 0.02 in 1982 / 100,000 population (26 cases). The neonatal tetanus mortality rate dropped even faster, from 361,000 live births (972 cases) in 1947 to 0.67 (13 cases) in 1970 to 0 in 1979. The neonatal tetanus mortality rate The rapid decline is closely related to the birth of newborns in hospitals instead of birth at home, during which no tetanus immunizations for pregnant women. The reduction in neonatal tetanus mortality led to a decrease in total mortality from tetanus.