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目的研究病灶性新皮质癫癎发作间期MEG和MRI一致性与预后的关系。方法 23例病灶性新皮质癫癎接受了术前评估及手术治疗,所有患者术前均接受MEG检测,数据分析处理采用等价电流偶极子(ECD)法和合成孔径法(SAMg2)。7例患者接受了颅内电极植入后长程视频皮层脑电图监测。术后随访一年以上并运用Engel法评价预后。结果 MEG与MRI一致的病例手术有效率(Engel class I or Ⅱ)及术后无发作率(Engel class IA)均优于不一致者。结论病灶性新皮质癫癎,MEG结果与MRI结果一致时手术效果良好,对此类病例不需要再进行颅内电极植入行癫癎灶定位,颅内电极植入仅适用于MEG结果与MRI结果不一致的病例或需要功能区定位者。
Objective To study the relationship between MEG and MRI consistency and prognosis in focal neocortex epileptic seizure. Methods Twenty - three patients with focal neocortex epilepsy underwent preoperative evaluation and surgical treatment. All patients underwent MEG preoperatively. The data were analyzed using the equivalent current dipole (ECD) method and the synthetic aperture method (SAMg2). Seven patients underwent long-range video cortical EEG monitoring after intracranial electrode implantation. The patients were followed up for more than one year and evaluated by Engel’s method. Results The EEG (Engel class I or II) and Engel class IA (MEG) were superior to those of the inconsistent MRI. Conclusion The results of neovascular epilepsy and MEG are consistent with those of MRI. The operative results are good when the result of MRI is consistent with the results of MRI. No intracranial electrode implantation is needed in this kind of cases. The intracranial electrode implantation is only applicable to the results of MEG and MRI Inconsistent cases or need function locator.